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Author Topic: Low Dose Naltrexone  (Read 16594 times)
searchingforcure11
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« Reply #30 on: September 23, 2010, 08:11:41 PM »

I never had a wet dream in my entire life.  But orgams were perfect up till about 22.  So it seems like there is really no correlation.  I just think I get myself off too much to have a wet dream.  If you are always ejaculating then it probably is tougher to have a wet dream.  Since I reached puberty and knew the feeling of sex I never really went longer then a week without getting myself off and on average every day or every other day.  I wonder if getting off too much has anything to do with it.  So I agree I dont think not having wet dreams really has any correlation to our problem.  I have to say the last time I really really felt normal sexual functioning was a little over a year ago when I took this sex pill with yohimbe.  It was incredible.  It didnt work every time though.  The first few times I took it it was the most amazing orgasms just like it used to be.  The problem is that that stuff makes you get chills, heart racing, and you cant sleep for like 10 hours.  But it proved to me it was possible to feel that feeling again. 
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researcher
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« Reply #31 on: September 23, 2010, 08:59:03 PM »

thats intersting you mention yohimbe

the guys on the propecia board were talking about it as well.

http://www.propeciahelp.com/forum/viewtopic.php?f=23&t=2295
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NoFun
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« Reply #32 on: September 23, 2010, 09:39:49 PM »

Like the guy at the finasteride site, the first time I took yohimbine, I had a big WOW reaction. I seemed very sensitive to the effects, and wouldn't take anywhere near the usual dose, but still have a positive reaction.

As the years went by, the positive side of the reaction has dimmed, leaving only the negatives - difficulty sleeping, chills, agitation, and increased heart rate. During sex, the positives are more than worth it, but the negatives just last too long for me, and I don't take it anymore. If I could find something that gave the effects of yohimbine, but only lasted a couple of hours, I'd use it all the time for sex.

Note that it never gave me orgasms, but it helped with erection, arousal, and ejaculation.
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michaelsad
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« Reply #33 on: September 23, 2010, 09:50:49 PM »


Don't know the progress with abcde,  I hope he will share with us experiement updates with his few medicines.   
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NoFun
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« Reply #34 on: September 24, 2010, 02:00:51 PM »

I picked up my naltrexone prescription last night, and took only 1.5mg to start slow and see if the endorphin blockade had any immediate negative side effects. None.  I stayed up an hour and a half after taking it to test out how the blockade felt, and I felt nothing.

In the morning, a slightly more aroused morning than usual, but nothing big.

I'll try more tonight; either 3.0 or 4.5 mg.
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lostmojo
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« Reply #35 on: September 25, 2010, 07:54:55 AM »

Very interested to hear your updates NoFun, I'm glad you finally have some Naltrexone.

If the Viagra does not help (have not tried it yet) I'm interested in trying supplements that are supposed to dampen sexual response. Given that none of the supplements that are supposed to heighten sexual response have done anything for me I think it would be worth a try with the opposite, I really have very little to lose.

Could you suggest some "dampening" supplements please NoFun? I think the methodology is to have them at quite low doses, less than would be had when used for the traditional intended effect. I think we need to start thinking more outside the box. Apart from some members of the SSRI group with GABA Plus we're not making significant progress.
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NoFun
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« Reply #36 on: September 25, 2010, 11:29:08 PM »

Could you suggest some "dampening" supplements please NoFun? I think the methodology is to have them at quite low doses, less than would be had when used for the traditional intended effect. I think we need to start thinking more outside the box. Apart from some members of the SSRI group with GABA Plus we're not making significant progress.
Dampening supplements? That is outside the box. I like it.  Never seen a supplement ad "Kill your sex drive! Order SexAway today!" I'll have to think about that.

The antidepressant supplements for boosting serotonin, such as 5-htp, would be a possibility. For me, it worked more or less as expected, killing sex drive. The various anti-dht supplements used for prostate health would be another dampening supplement. Saw Palmetto.

Another possibility is taking phyto estrogens. The idea is to take a lot of weak estrogen agonists that compete with estrogen at the estrogen receptors and upregulate the enzymes that metabolize estrogens.  I never looked into that much, so I don't have supplements to recommend there, but it seems a reasonable theory.
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lostmojo
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« Reply #37 on: September 26, 2010, 02:11:06 AM »

Could you suggest some "dampening" supplements please NoFun? I think the methodology is to have them at quite low doses, less than would be had when used for the traditional intended effect. I think we need to start thinking more outside the box. Apart from some members of the SSRI group with GABA Plus we're not making significant progress.
Dampening supplements? That is outside the box. I like it.  Never seen a supplement ad "Kill your sex drive! Order SexAway today!" I'll have to think about that.

You and I are going into business together NoFun. Two of the evergreen markets that always sell are sex and making money. We will market SexAway as a money making product...

"How many times has sex got in the way of you making as much money as you want? Now with new SexAway you won't ever be distracted by sex again. No erections, no desire, you'll be a 24/7 dedicated money making machine and never have money worries ever again. Napoleon Hill author of 'Think and Grow Rich' spoke of the 'The Mystery of Sex Transmutation' well why wait until you get older to learn how to harness your sexual powers to accumulate wealth when you could start today with SexAway!"

The antidepressant supplements for boosting serotonin, such as 5-htp, would be a possibility. For me, it worked more or less as expected, killing sex drive. The various anti-dht supplements used for prostate health would be another dampening supplement. Saw Palmetto.

What I would be looking for is 5-htp to increase sexual desire contrary to the usual experiences, obviously if libido were decreased by taking 5-htp then that is not helpful. I am willing to give it a try if taking Viagra doesn't improve anything.

Many of us have been trying to boost acetylcholine levels with very little success, why not try some stuff that is meant to decrease acetylcholine levels and see what happens? That is the sort of thing I'm suggesting to try.

Many of the traditional sexual enhancers are supposed to increase blood flow to the genital area, I am not suggesting to try decreasing blood flow that would be stupid. But things such as trying a contrarian approach to neurotransmitters I think are worth trying. After all with me the less sensation I feel from a sexual position the worse my PE gets, this is upside down, if I can barely feel it why is it causing an almost uncontrollable reaction? So why not try an upside down approach elsewhere.
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searchingforcure11
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« Reply #38 on: September 26, 2010, 03:06:23 AM »

why would you want to dampen sex drive?  Just take antidepressants then because they will make you not want sex because there is no feeling at all.  Till the day I die I will constantly look for a cure.  I dont let it bother me now if i dont have a great orgasm I just think about it as oh well.  Sometimes I get some feeling and that is kinda nice and some pleasure comes out of it so have to look at the bright side of things.
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lostmojo
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« Reply #39 on: September 26, 2010, 04:53:58 AM »

why would you want to dampen sex drive?

The intention is not to try and dampen sex drive but to increase it. Because I've tried so many things that are supposed to increase sensation/sex drive and haven't I thought it was worthwhile trying things that are supposed to dampen and hope that they have the opposite effect.
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NoFun
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« Reply #40 on: September 26, 2010, 04:26:15 PM »

You and I are going into business together NoFun. Two of the evergreen markets that always sell are sex and making money. We will market SexAway as a money making product...
...
But things such as trying a contrarian approach to neurotransmitters I think are worth trying.
...
After all with me the less sensation I feel from a sexual position the worse my PE gets, this is upside down, if I can barely feel it why is it causing an almost uncontrollable reaction? So why not try an upside down approach elsewhere.
You have a real point with SexAway. There would be a lot of applications.

I get the contrarian approach idea.

I'd go further and say it is likely that those with premature ejaculation require a treatment to dull sexual response, not enhance. I don't think I'd ever dull on the the hormone side, but on the neurotransmitter side, it makes a lot of sense.

What I say comes from my perspective, of having limited sensitivity, poor erections, and delayed ejaculation. I haven't looked into PE much, because it aint my problem.

I also like your idea of trying stuff to see what happens. Consider anything you take as a probe that will tell you something about how you operate. In particular, pay attention to anything you are very sensitive to, like I am to yohimbine.

Again, on the contrarian tact, I've heard it argued that if you have an unusually large *negative* initial reaction to an anti depressant, that you should stick with it, because it demonstrates that you're hitting part of your system that has too much sensitivity, and continued stimulation will eventually downregulate that sensitivity.
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NoFun
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« Reply #41 on: September 26, 2010, 04:29:08 PM »

After a couple of days at 4.5 mg before bed, I don't fell much of any effect, positive or negative.

The first day, when I only took 1.5mg, I did feel extra randy, with improved erections. Maybe I'll go back to a low dose for a while.
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lostmojo
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« Reply #42 on: September 27, 2010, 07:34:29 AM »

Again, on the contrarian tact, I've heard it argued that if you have an unusually large *negative* initial reaction to an anti depressant, that you should stick with it, because it demonstrates that you're hitting part of your system that has too much sensitivity, and continued stimulation will eventually downregulate that sensitivity.

Interesting. The Urologist I saw did not think that SSRIs were an obvious candidate to try for AE but he said if they were used it should be in much smaller doses than is typical for their normal applications.
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NoFun
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« Reply #43 on: September 27, 2010, 01:33:23 PM »

Interesting. The Urologist I saw did not think that SSRIs were an obvious candidate to try for AE but he said if they were used it should be in much smaller doses than is typical for their normal applications.
SSRIs are a recognized treatment for PE. I'm not sure if you take them only before sex, all the time, or either.

It is reasonable to think that if you fix the PE, maybe you can fix the AE as well. With PE, you may not be getting enough of a buildup to have a decent orgasm.
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NoFun
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« Reply #44 on: October 03, 2010, 11:07:58 PM »

I've fiddled with the dose, going from 1.5mg to 3.0mg.

I've been in a continuous stressful situation lately, so this isn't the best controlled experiment. I've been feeling more motivated, and have been holding up under the stress well. So it may be helping me cope better, which has been a problem. I'm feeling a bit more resourceful, and acting the part too. These indications are too subjective and touchy feely for me to have too much confidence about them.

My sex drive is nowhere, but in a certain way that's good - I'm just less compulsive about it. Alan mentioned something similar when he cured himself. Sadly, I am not cured in any way. Besides this ambiguously positive result, I have slightly more forceful ejaculations, and probably more and thicker ejaculate. A slight improvement, and it may be more due to relative abstinence from masturbation, but I think it is objectively true.

Otherwise, nothing too exciting to report. No other noticeable effects. Except maybe less obsessing over our problem. Maybe I was too busy.

I encourage others to give it a try. A month's dose, with insurance paying half, was $23 for me at Walgreens. I think you can get it without insurance for that price. People try a lot of magic potions and elixirs for sexual dysfunction, but few have tried this, and it actually has some research to back up improved orgasms.

I will continue to update this thread with status reports periodically.
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